From the Journal

A 4-year-old boy is admitted with a 2-week history of high fever with rigors; profuse night sweats; progressive upper quadrant pain; and diarrhea.

More than 60% of male adolescents will experience gynecomastia—a physiologic increase in stromal and glandular breast tissue.

Extensive ecchymoses following a fall, palmar hyperpigmentation, unusual pigmentation pattern on thigh

A 17-year-old girl presents, on crutches, with left knee pain from an injury she sustained during a flag football game the previous night.

A 20-year-old woman presents with lower abdominal pain of 9 months’ duration. The pain is bilateral in the lower quadrants, dull, constant, and nonradiating.

Becker nevus, solitary and multiple café au lait macules, Fanconi anemia, urticaria pigmentosa, McCune-Albright syndrome, segmental café au lait macule, pigmentary mosaicism, Proteus syndrome

An 85-year-old woman who resides on the dementia unit of a nursing home is seen for routine care.

Have you seen these particular manifestations of sarcoidosis, rheumatoid arthritis, colon and other cancers, diabetic vasculopathy, hyperlipidemia, and zinc deficiency?